The role of innovation and knowledge in the process of changing our economic landscape is a topic of much interest in Economic Geography as well as in the current policy discussion as illustrated by the Europe 2020 strategy. A substantial part of the theoretical inspiration in this field comes from Economics as exemplified by the growth of New Economic Geography and the current "evolutionary turn" in Economic Geography.

Innovation, knowledge and territoriality is currently one of the active cores of theoretical and empirical work economic geography development. What is missing is a corresponding development of  "time-space sensitive" methodologies that allows for geographers to collect, analyse and visualize continuous processes of change unrestricted by pre-set spatial scales of analysis

The aim of this paper is to illustrate how time-geography can contribute to a better understanding of territorial knowledge dynamics using a biographical methodology. Focus is on knowledge per se and its flows in space-time from a micro perspective.

An initial overview of knowledge and time in Economic Geography is followed by a brief description of the innovation biography methodological approach. Then time-geography and its basic components are presented. The final part of the paper focuses on the theoretical and practical potentials and limitations of combining the time-geography framework with a biographical approach to territorial innovation and knowledge studies.