The ability and capability to interact and communicate have become an absolute requirement and a basic resource for most firms and economic activities. In the process of globalisation and transnationalisation of markets and firms the ability to interact over long distances becomes a particularly critical concern. This paper discusses firms’ strategies, capabilities, means and practises for transnational and wide-reaching interactions. A particular interest is aimed toward intra-organisational interactions and to knowledge intensive companies. The paper discusses the role of institutions and of social network and perceptions among individual actors for how transnational and global interactions of firms develop.